After you have obtained 8 gym badges, in Pokemon Black and Pokemon White versions, you will have the ability to battle the Isshu region Elite Four. These four trainers are one of the strongest trainers in the game. The names of these trainers are the Shikimi theGhost -type Elite Four member, next is Giima the Dark-type Elite Four, then it's Caitlin the Psychic-type Elite Four, and last Renbu the Fighting-type Elite Four they will have no champion at first but later in the game you will fight Adeku.
| Name | Black and White | Type | First Battle | Rematch |
| Shikimi | Image:ShikimiBWsprite.png | Ghost | ||
| Giima | Dark | |||
| Caitlin | Psychic | |||
| Renbu | Fighting |