Differences between the Anime and Manga
- Ash Ketchum's clothes were completely different from the anime and it appears to be more like based on Red's attire from the video game series.
- Gary Oak has a sister in the manga and she was named May Oak instead of Daisy Oak from the video game version, that might avoid the conflict with Misty's sister.
- The scene from To Evolve or Not to Evolve, That Is the Question! in the Hot Springs that shown Misty naked that was completely removed by VIZ Media in North America. This is due to containing adult content and nudity which is considered unsuitable for international audiences.
- In the epilogue of the final chapter of Volume 4, James and Jessie are shown to be married and had a kid together sometime later.