The Soothe Bell is an item which, when given to a Pokémon to hold, will double the amount of happiness it gains. This can make certain Pokémon evolve faster. In Pokémon Diamond, Pearl, and Platinum, it can be obtained inside the Pokémon Mansion on Route 212. In HeartGold and SoulSilver, it is obtainable in the National Park.
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In Pokemon Best Wishes, Season 2 episode 21, is used to calm a Wild Dustdas that was attacking to Pikachu and Kibago.