Solosis is a small spherical Pokémon that has the appearance of a single cell; it levitates using its psychic powers. Its lime green rounded body (nucleus) is encased by cytoplasm and a translucent green membrane. It has two small black spots for eyes, and it appears to have a red rhombus-like opening for a mouth. It has a curly yellow spring-like appendage on top of its head, connected to its nucleus.
Solosis is the first Pokémon to be based on cellular structure/cells.
The nucleus is similar to the shape of a brain.
Solosis is probably green colored because the substance surrounding it could be filled with chlorophyll, causing it to possibly use photosynthesis for food. Despite this, it is not a Grass-type. Because their bodies are enveloped in a special liquid, they are fine in any environment, no matter how severe.
Solosis is based on a cell.
Its name appears to be a play on "mitosis" which is the splitting of cells to produce two identical cells, and "solo", meaning singular.