Drapion is a powerful Pokémon, and was able to take out 3 of Ash's Pokemon in a row. It was Paul's third Pokemon against Ash, after he had defeated Aggron and Gastrodon without losing a single Pokemon.
In Familiarity Breeds Strategy!, it taks action quicky and grabs Buizel with it's tail. The batle continues in A Real Rival Rouser!, and Drapion blocks SonicBoom by grabbing Buizel's tail with a free hand, it but Buizel escaped by inflating his floatation sac and then blasting Drapion with Water Gun whilst propelling himself into the air at the same time. However while it was in the air, Drapion used Toxic Spikes and as soon as Buizel landed it was poisoned and Drapion finished it with Pin Missile.
Drapion then defeated Ash's Staraptor quickly and easily by dodging Aerial Ace at the last second and grabbing it with it's tail. It then uses Cross Poison and slams it into the Toxic Spikes, fainting it.
Despite being affected by Toxic Spikes right off the bat, Ash's Torterra put up a good fight by blocking Cross Poison with Energy Ball and hitting it with Leaf Storm. However, Pin Missile was able to nullify a second Leaf Storm, which marked the turning point of the battle. Drapion grabbed Torterra while it was attempting to use Rock Climb and used Poison Fang. Torterra fully healed itself with Synthesis, but Drapion knocked it out with one supereffective Pin Missile before being recalled, which gve Paul a 4-3 lead.
Drapion appeared at the end of the same episode in to fight Ash's Gliscor after Paul's team had been reduced to 2, while Ash still hadn't lost another Pokemon since his last battle with Drapion. While Drapion took out 3 of Ash's Pokemon without much trouble, Gliscor was more unpredictable and gave Drapion some trouble. Drapion deflects Stone Edge with Cross Poison, but Gliscor hit Drapion with Giga Impact, and flew into the sky to recharge safley. Drapion fires Pin Missile, but Gliscor goes for an X-Scissor, ending the episode. In the next episode, Drapion hits blocks X-Scissor at the last moment, and plants a devastating hit with Pin Missile. Gliscor goes in for a Fire Fang attack, and while Cross Poison narrowly hits it, Fire Fang lands. While Drapion is able to quickly slam it into the ground, Fire Fang burns Drapion with which angers Paul, and excites Ash. The burn damage overwhelms the Ogre Scorp Pokemon, and Drapion was finally defeated.
|Pin Missile +||Familiarity Breeds Strategy!|
|Cross Poison +||Familiarity Breeds Strategy!|
|Toxic Spikes||A Real Rival Rouser!|
|Poison Fang +||A Real Rival Rouser!|
|+ indicates this Pokémon used this move recently.*|
- indicates this Pokémon normally can't use this move.
- Paul was seen attempting to catch a Drapion with his Electabuzz in Chim-Charred but it escaped. It is unknown whether this is the same Drapion.