She and her Purrloin were very close. One day, she went out but never came back. Since the day her Purrloin ran off she has been looking for him. She found Cilan who found her Purrloin. When she found him he explained that on her way she broke her arm and couldn't come back but Purrloin didn't believe her. When she tried to save the others Purrloin came back with Tranquill and loved her again. After the ordeal she shocked Meowth and Oshawott by revealing the fact that her Purrloin was male.
Misha's Purrloin first appears when he steals some berries from a group of Tranquill, whom proceed to pursue the group. It is here that Meowth becomes infatuated with him, in the false belief that Purrloin was female. In turn, Ash's Oshawott also falls in love with Purrloin, causing a falling out between the two Pokémon. Purrloin uses this event to his advantage in order to get them to win "her" affections, as well as to steal berries from Ash. When Purrloin encounters his trainer Misha, he proved that he still cared for his Trainer and apologized to Ash.