Meloetta was first pursued by Team Rocket in Virbank City. It was able to elude them but somehow made its way into the Pokestar Studios where Ash had encountered it. After he saved it from a collapse of some tools it stayed close behind him, following him to Virbank Gym.
Meloetta appeared again in All for the Love of Meloetta! where it was attacked by Team Rocket who had Woobat and Yamask attack it with Air Slash and Shadow Ball, respectively. Meowth then tried to catch it in an electric net but it was able to make it's escape. However, it was injured in the process and wandered into the street in a daze, almost getting run over by Cynthia's vehicle. Ash was able to recognize Meloetta from before and Cynthia applied potion to its wounds. Then they attempted to get its fever down with a bag of ice. While Iris and Cilan searched for an Oran Berry for it, Ash kept watch.
After a little bit Oshawott came out of his Poke Ball sensing Meloetta's presence and instantly fell in love with it. Meloetta recovered a bit after eating an Oran Berry Emolga brought. During this time both Emolga and Oshawott were arguing with each other and Meloetta began to sing in order to calm them down. Afterwards, it disappeared once more but it had followed Ash and the others to Cynthia's jet.
In Piplup, Pansage and a Meeting of the Times!, it followed Ash and snuck into Jeremy's car to Cynthia's villa. When Ash sees a Rattata, Meloetta appears and sits on Ash's lap. Seeing Ash, Meloetta seems very excited, when Cynthia says that Meloetta must really like Ash. A while later, they arrive at Cynthia's villa, but when Jeremy opens the door, Meloetta suddenly disappears again. A while later, when Ash and co. let their Pokemon see their old friends Dawn and Piplup her pokemon, Meloetta secretly comes. The Pokemon can sense Meloetta, and Ash knows it's nearby and calls it out to meet Dawn. Meloetta appears and Dawn get acquainted. Upon seeing Meloetta, Dawn's Piplup instantly fall in love with it just as Ash's Oshawott before it. Oshawott attacked him with Aqua Jet, upset to see Piplup and Meloetta gettting along, sparking a rivalry. During the battle between Dawn's Piplup and Cilan's Pansage, Meloetta was excited about the battle and was happy for Piplup.
In BW098 and BW099, Giovanni returned to spearhead Team Rocket's: Operation Tempest, a stratagem which involved caputuring Meloetta. He did just this using goggles created by Dr. Zager to be see the mythical Pokémon even when she was invisible. Giovanni quickly defeats Ash and rejoins Jessie, James, Meowth and Zager. Team Rocket led Giovanni to the Abyssal Temple which they had spent a while looking for. With Ash & Pikachu captured, Giovanni uses Meloetta to summon the Reveal Glass and rise the Abyssal Temple, using Meloetta's Calming Song, that Team Rocket had insidiously recorded during her time with Ash. Meloetta is caused to suffer in this ceremony. The Kami trio are summoned and the Reveal Glass morphs them into their, feral, viscious Therian Formes. At Giovanni's command, they battle the resistance created by the escpaed Ash, Pikachu and their friends, Iris' Dragonite leds this resistance. In the midst of a titanic battle, Ash and Pikachu confront Giovanni. Ash orders Pikachu use Electro Ball, because Piakchu had been charged up from an earlier attack, the Electro Ball's size and power are augmented significantly. The electric attack incinerates the platform Giovanni was standing on and severes the link between the sadistic leader and the tortured Meloetta. However Giovanni loses his mind because of this ordering the Kami trio to destroy the Unova region. Jessie, James and Meowth throw themselves at their beloved boss and succesfully save him, not only from a fatal explosion but from his insane state. Team Rocket then make a total retreat to Kanto.
Larry takes control of the Reveal Glass and with Meloetta's Calming Song, calm the Kami trio, revert them back to their Incarnate Formes and back to where they belong. Larry as Meloetta's guardian leaves with her after a final goodbye to Ash and friends.
|Relic Song||Sing Meloetta: Search for the Rinka Berries|
|Close Combat||Expedition to Onix Island!|
|+ indicates this Pokémon used this move recently.*|
- indicates this Pokémon normally can't use this move.
- In the preview of the next Team Rocket arc, Meloetta is revealed to have some kind of connection to the Abyssal Ruins, as well as Tornadus, Thundurus, and Landorus in their Therian formes.