Kyurem is one of the stars and the main antagonist of Pokémon the Movie: Kyurem vs. the Sword of Justice.
When Keldeo brashly challenges Kyurem to a battle, it dominates the fight, easiy deflecting or dodging Keldeo's attacks, and the Boundary Pokémon ultimately breaks off Keldeo's horn with Shadow Claw. When Terrakion attacks Kyurem with Hyper Beam in an attempt to defend Keldeo, Kyurem deflects it then freezes the Swords of Justice with Ice Burn to prevent them from interferring with the battle. Keldeo then runs away during the middle of the fight out of fear, and Kyurem gives chase, determined to finish their battle.
Kyurem pursues them and attacks them several times, only for them to be distractioned by Iris and Cilan. Eventually, Keldeo and Kyurem face off where they first met, and, despite Keldeo giving it its all, Kyurem retains the upper hand until Keldeo learns the move Secret Sword. When protecting its friends from a stray Freeze Shock attack, Keldeo takes major damage, making Kyurem the victor. Instead of finishing the battle, however, Kyurem respects Keldeo's courage and states that it was better to lose a battle than to lose one's friends.
|Ice Beam +||Kyurem vs. the Sword of Justice|
|Dragon Pulse +||Kyurem vs. the Sword of Justice|
|Shadow Claw +||Kyurem vs. the Sword of Justice|
|Ice Burn +||Kyurem vs. the Sword of Justice|
|Freeze Shock +||Kyurem vs. the Sword of Justice|
|+ indicates this Pokémon used this move recently.*|
- indicates this Pokémon normally can't use this move.
He is the second movie antagonist to be a Pokémon, the first being Mewtwo.