While heading to Olivine City Ash and co. notice a huge blimp fly by. When they got to the landing strip they saw the captain of the Blue May, a cruise in the sky, says that two Pokémon belonging to two lovely, rich and friendly ladies are ill. Brock is up to the task and saves the day by curing the Pokémon of whatever's ailing them. What kind of Pokémon are these? Did they come from an entirely different region?
This is the first episode to feature a Generation III Pokémon before Generation III was invented and before Generation III Pokémon transcended from Hand-drawn Cel animation, to computer cel animation.
This was the first episode to have "Boss Fantasies". This lasted until Season 14 (Black and White).