All members of the Hexagon Brothers are known for having words associated with colors in their name due to their appearance. Their appearance also goes with the type of Pokémon they will use in battle.
- Resix: Uses mainly Fire-type Pokémon
- Blusix: Uses mainly Water-type Pokémon
- Browsix: Uses mainly Ground-type Pokémon
- Yellosix: Uses mainly Electric-type Pokémon
- Purpsix: Uses mainly Poison-type Pokémon
- Greesix: Uses mainly Grass-type Pokémon
The Hexagon Brothers are first seen at the Cipher Lab where Resix orders a head count. However, they mistakenly count five members and decide to wait for the other member to show up. Michael eventually appears and the Hexagon Brothers spot him. Battling the Hexagon Brothers is completely optional and Michael can just simply head into the lab. However, Michael will miss out on valuable Shadow Pokémon that he can add to his team.
The Hexagon Brothers are seen again in Phenac City where they all impersonate the the Pre Gym Leader: Justy. Like before, Michael doesn't have to battle the Hexagon Brothers but Michael will miss out on experience points for his team. The Hexagon Brothers will use stronger Pokémon at this point and will even use their uncaptured Shadow Pokémon from earlier.
Cipher Lab (First Encounter)
- Oddish (Lv. 9)
- Cacnea (Lv. 9)
- Shroomish (Lv. 9)
- Lotad (Lv. 8)
- Pineco (Lv. 9)
- Shadow Seedot (Lv. 17+)
The Hexagon Brothers are often view as a parody of the Power Rangers.