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The DNA Splicers is a key item that allows the player to merge Kyurem with either Zekrom or Reshiram into Black Kyurem or White Kyurem, depending on version. Once the merge is complete, the pin can also be used to revert Black Kyurem or White Kyurem into two separate Pokémon. It works with both groups (Reshiram and Kyurem, Zekrom and Kyurem) in both games. You cannot use it on two Kyurems in one game (cannot create both Black Kyurem and White Kyurem within one game) Game of Origin: Pokémon Black 2 and Pokémon White 2. It is dropped when the player catches Kyurem in Giant Chasm. (The DNA Splicers will remain there until the player picks it up.)
It is given to the player in Opelucid City, where Drayden, the Gym Leader, gives it to the player. The pin is then stolen by one of the Shadow Triad of Team Plasma. The player fights the Shadow Triad, who states that she/he was actually buying time for the other two to escape with the DNA splicers.
Two Pokémon can be fused together, Kyurem with either Zekrom or Reshiram, both Zekrom or Reshiram can not be fused together at once. No other Pokémon can be fused with this item. There are two versions of Kyurem White Kyurem (Reshiram), and Black Kyurem (Zekrom).
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