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Brendan may refer to:
- Brendan, a character in the Pokemon anime.
- Brendan, the rival or playable character in Generation III games.
- Brendan, a character in Pokémon Omega Ruby and Pokémon Alpha Sapphire Animated Trailer
- Ruby, Brendan's counterpart in the Adventures manga.
- Brendan, a character in the Pokémon Generations.
- Rald, Brendan's counterpart in the Battle Frontier manga.
- Alpha and Omega, two of Brendan's counterparts in the Pokémon Omega Ruby Crimson Passion and Pokémon Alpha Sapphire Indigo Wisdom manga.