Audino is a plump bipedal creature with a cream and pink colored body. It has large ovular blue eyes and frilly pink and cream ears; long, extendable curled feelers are attached to its earlobes. The curled feelers on its ears allow Audino to listen to the heartbeats of others and determine their state of health. The pink pattern on its body resembles a coat, and it has a pudgy cream-colored belly and underside. Its small paws with three digits are cream colored, and it has short legs with small two-toed feet. There are pink heart-shaped patterns on the bottoms of Audino's feet. It has a white fluffy tuft for a tail.
Mega Audino has a significantly more angelic look. Most of its body is pure white, and it appears to be wearing a frilly lab coat, similar to a doctor. It has larger frilled ears with cream-colored tips that stand upright, and long swirled feelers extending from its lobes. Beneath its white "lab coat" its plump belly is cream-colored. Its face is cream colored, as well, and it has ovular bright red eyes. It has a larger fluffy white tuft for a tail, and it appears to have a similarly-shaped tuft on its chest. There is a long curly white appendage attached to the tuft on its chest, which it holds in its paw (so far the function of this new feeler is unknown). It appears to be wearing white boots with wing-like tips.
Audino does not evolve normally. Audino obtains a mega evolution in Omega Ruby and Alpha Sapphire by using a Mega Stone.